Plant biology

Peptide Regulators of Plant Development

Science's STKE  15 Aug 2006:
Vol. 2006, Issue 348, pp. tw279
DOI: 10.1126/stke.3482006tw279

Cell-cell communication is essential for organized tissue formation. Recently, a role for peptides in plant development has been established. In the shoot apical meristem of Arabidopsis, cell fate determination involves the CLAVATA3 gene, which encodes a putative peptide ligand, and the CLAVATA1 gene, which encodes a leucine-rich repeat receptor-like kinase. However, the precise identity of the individual signaling peptide has remained elusive (see the Perspective by Simon and Stahl). Two independent groups, Ito et al. and Kondo et al., have now isolated specific CLAVATA-derived 12-amino acid peptides involved in the regulation of plant meristem development.

R. Simon, Y. Stahl, Plant cells CLEave their way to differentiation. Science 313, 773-774 (2006). [Summary] [Full Text]

Y. Ito, I. Nakanomyo, H. Motose, K. Iwamoto, S. Sawa, N. Dohmae, H. Fukuda, Dodeca-CLE peptides as suppressors of plant stem cell differentiation. Science 313, 842-845 (2006). [Abstract] [Full Text]

T. Kondo, S. Sawa, A. Kinoshita, S. Mizuno, T. Kakimoto, H. Fukuda, Y. Sakagami, A plant peptide encoded by CLV3 identified by in situ MALDI-TOF MS analysis. Science 313, 845-848 (2006). [Abstract] [Full Text]