Differentiation of PC12 Cells

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Science's STKE  05 Sep 2006:
Vol. 2006, Issue 351, pp. tr9
DOI: 10.1126/stke.3512006tr9

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This 3-week-long series of collaborative laboratory exercises explores how to use a cultured cell system (PC12 cells) to study signaling pathways involved in cellular differentiation. The laboratory would be useful in a neurobiology or cell biology course for advanced undergraduate students. The background and details for performing the lab are provided along with suggestions for assessing student performance and understanding.

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