Vol 2007, Issue 388
- The Impact of X-ray Crystallography and NMR on Intracellular Calcium Signal Transduction by EF-Hand Proteins: Crossing the Threshold from Structure to Biology and Medicine
Analysis of EF-hand proteins in complexes with their targets may define the structural basis for functional consequences.
- Parsing the Motion of Single Molecules: A Novel Algorithm for Deconvoluting the Dynamics of Individual Receptors at the Cell Surface
A new statistical method helps distinguish a protein moving with a purpose from a protein on a random walk.
A repressor protein in Escherichia coli spends about 90% of its time diffusing along DNA, falling off, and trying again if it does not find its specific binding site within 5 milliseconds.