Contents

05 June 2007
Vol 2007, Issue 389
  • Contents

    • Perspective

    • Protocol

    • Editors' Choice

      • Silencing Cell Death?

        A decrease in DAPK1 activity may enhance susceptibility to chronic lymphocytic leukemia.

      • Shore Up That Wall!

        Phosphorylation of the enzyme that produces UDP-glucose redirects synthesis to the cell periphery to increase wall glucan synthesis at the expense of glycogen synthesis.

      • Diet of Worms

        The longevity of C. elegans induced by a restrictive diet is mediated by the transcription factors PHA-4 and SKN-1.

      • Virulent Protein Kinase A

        Yersinia protein kinase A targets Gα to promote pathogenicity.

      • Not Like Peas in a Pod

        Two species of nitrogen-fixing bacteria lack the usual liposaccharide signal by which they communicate with their legume hosts and instead may use a purine derivative.

      • Let the RNA Do Its Business

        An abundant viral RNA stabilizes host mitochondria and thus prevents infection-induced cell death, ensuring that the host cell survives long enough for the virus to reproduce.

      • Designer Proteasome

        A proteasome found only in cortical epithelial cells of the thymus has a specific protein-cleaving subunit that may contribute to positive selection of developing immune cells.

About The Cover

Cover image expansion

COVER This week features a Protocol on detecting protein interactions with capture beads and flow cytometry. [Image: Christopher Bickel, AAAS]