ReviewImmunology

A Role for the Cytoplasmic Adaptor Protein Act1 in Mediating IL-17 Signaling

Science Signaling  07 Aug 2007:
Vol. 2007, Issue 398, pp. re4
DOI: 10.1126/stke.3982007re4

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  1. Article
    1. Abstract
    2. The Interleukin-17 Cytokine Family
    3. Physiology and Pathology of IL-17
    4. Cellular Sources of IL-17
    5. Receptors for IL-17
    6. The Identification of Act1 as a Signal Transduction Protein
    7. Act1 as a Unique Adaptor Protein for IL-17R
    8. Potential Pathogenic Relevance of Act1 in IL-17 Signaling
    9. Act1-Independent IL-17 Signaling?
    10. Concluding Remarks
    11. References
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