Contents

21 August 2007
Vol 2007, Issue 400
  • Contents

    • Editorial Guide

    • Perspective

    • Review

    • Protocol

    • Editors' Choice

      • Osteocytes Losing Their Grip?

        Glucocorticoids elicit osteocyte apoptosis by inhibiting cell adhesion.

      • Notch Sees Clearly

        Notch1 links vitamin A metabolism to the maintenance of a healthy cornea.

      • XRab40 Participates in a Ubiquitin Ligase Complex

        XRab40 participates in a Cullin-based ubiquitin ligase complex that regulates noncanonical Wnt signaling and plays a critical role in Xenopus gastrulation.

      • A Moving Story

        G proteins move between the plasma membrane and internal membranes.

      • Hold Them Back

        14-3-3 proteins are required to inhibit the activity of brassinosteroid-dependent transcription factors.

      • Fleeting Memories

        Even long after consolidation of a stable memory in rats, the activity of a particular protein kinase isoform is required in the cortex for its persistence.

      • Smell the CO2

        Mice can sense near-atmospheric concentrations of CO2 using a subset of olfactory neurons that may use the catabolic enzyme carbonic anhydrase.

      • Understanding Selective Synapse Elimination

        In developing worms, the pruning of excess synapses requires proteasome-mediated protein degradation and is selectively prevented by a neural adhesion molecule.

About The Cover

Cover image expansion

COVER This week's Focus Issue on cell migration features an Editorial Guide, as well as a Perspective, a Review, and a Protocol. The image depicts a cell extending a pseudopod toward a chemoattractant. [Image: Preston Huey, AAAS]