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Online Cover: This week features a Research Article that describes the crystal structure of the calcium/calmodulin (CaM)–dependent protein kinase (CaMK) death-associated protein kinase (DAPK) in association with CaM. When in a complex with DAPK protein, CaM adopted an extended conformation that was different from that adopted by CaM bound to a peptide consisting of the DAPK autoregulatory domain. The image is the structure of the DAPK-CaM complex. [Credit: Matthias Wilmanns, EMBL-Hamburg, Germany]

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882