Arabidopsis Jasmonate Signaling Pathway

Sci. Signal., 16 February 2010
Vol. 3, Issue 109, p. cm4
DOI: 10.1126/scisignal.3109cm4

Arabidopsis Jasmonate Signaling Pathway

  1. Aurélie Gfeller1,
  2. Robin Liechti2, and
  3. Edward E. Farmer1,*
  1. 1Current contributing authorities, Gene Expression Laboratory, Department of Plant Molecular Biology, Faculty of Biology and Medicine, University of Lausanne, Biophore, CH-1015 Lausanne, Switzerland.
  2. 2Former contributing authority, Swiss Institute of Bioinformatics, Vital-IT Group, Génopode, CH-1015 Lausanne, Switzerland.
  1. *Corresponding author. E-mail, edward.farmer{at}


Jasmonates control defense gene expression, growth, and fertility throughout the plant kingdom and have been studied extensively in Arabidopsis thaliana. The prohormone jasmonic acid (JA) is conjugated to amino acids such as isoleucine to form the active hormone jasmonoyl-isoleucine (JA-Ile). A series of breakthroughs has identified the SCF [SCF consists of four subunits: a cullin, SKP1 (S-phase kinase-associated protein 1), a RING finger protein (RBX1/HRT1/ROC1), and an F-box protein] CORONATINE INSENSITIVE1 (COI1) E3 ubiquitin ligase complex and the JASMONATE ZIM-DOMAIN (JAZ) proteins as central components in the perception of and transcriptional response to JA-Ile. JAZ proteins (most probably as dimers) bind transcription factors such as MYC2 before JA-Ile production. JA-Ile binds to COI1 to facilitate the formation of COI1-JAZ complexes, leading to ubiquitination and subsequent degradation of JAZ proteins. The degradation of JAZ proteins liberates transcription factors that function in the presence of the RNA polymerase II coregulatory complex Mediator to permit the expression of a number of jasmonate-regulated genes. Recent developments include the identification of COI1 as a receptor for jasmonates. Upstream of the signaling events, microRNA319 (miR319) negatively regulates the production of JA and JA-derived signals.


A. Gfeller, R. Liechti, and E. E. Farmer, Arabidopsis Jasmonate Signaling Pathway. Sci. Signal. 3, cm4 (2010).

Barley has two peroxisomal ABC transporters with multiple functions in {beta}-oxidation
G. M. Mendiondo, A. Medhurst, C. W. van Roermund, X. Zhang, J. Devonshire, D. Scholefield, J. Fernandez, B. Axcell, L. Ramsay, H. R. Waterham et al.
J Exp Bot 65, 4833-4847 (1 September 2014)

Loss of Plastoglobule Kinases ABC1K1 and ABC1K3 Causes Conditional Degreening, Modified Prenyl-Lipids, and Recruitment of the Jasmonic Acid Pathway
P. K. Lundquist, A. Poliakov, L. Giacomelli, G. Friso, M. Appel, R. P. McQuinn, S. B. Krasnoff, E. Rowland, L. Ponnala, Q. Sun et al.
Plant Cell 25, 1818-1839 (1 May 2013)

The Arabidopsis DELLA RGA-LIKE3 Is a Direct Target of MYC2 and Modulates Jasmonate Signaling Responses
M. Wild, J.-M. Daviere, S. Cheminant, T. Regnault, N. Baumberger, D. Heintz, R. Baltz, P. Genschik, and P. Achard
Plant Cell 24, 3307-3319 (1 August 2012)

RNA-Seq Analysis of a Soybean Near-Isogenic Line Carrying Bacterial Leaf Pustule-Resistant and -Susceptible Alleles
K. H. Kim, Y. J. Kang, D. H. Kim, M. Y. Yoon, J.-K. Moon, M. Y. Kim, K. Van, and S.-H. Lee
DNA Res 18, 483-497 (1 December 2011)

Ectopic Expression of AtJMT in Nicotiana attenuata: Creating a Metabolic Sink Has Tissue-Specific Consequences for the Jasmonate Metabolic Network and Silences Downstream Gene Expression
M. Stitz, K. Gase, I. T. Baldwin, and E. Gaquerel
Plant Physiol. 157, 341-354 (1 September 2011)

The JAZ Proteins: A Crucial Interface in the Jasmonate Signaling Cascade
L. Pauwels, and A. Goossens
Plant Cell 23, 3089-3100 (1 September 2011)

Jasmonate Controls Polypeptide Patterning in Undamaged Tissue in Wounded Arabidopsis Leaves
A. Gfeller, K. Baerenfaller, J. Loscos, A. Chetelat, S. Baginsky, and E. E. Farmer
Plant Physiol. 156, 1797-1807 (1 August 2011)

The Unfolded Protein Response Is Triggered by a Plant Viral Movement Protein
C. Ye, M. B. Dickman, S. A. Whitham, M. Payton, and J. Verchot
Plant Physiol. 156, 741-755 (1 June 2011)

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882