The TGF-β Signal Transduction Pathway

Sci. Signal., 27 April 2010
Vol. 3, Issue 119, p. tr4
DOI: 10.1126/scisignal.3119tr4

The TGF-β Signal Transduction Pathway

  1. Jack D. Thatcher*
  1. West Virginia School of Osteopathic Medicine, 400 North Lee Street, Lewisburg, WV 24901, USA.
  1. *E-mail, jthatcher{at}


This resource provides and describes two animated lessons that illustrate the transforming growth factor–β (TGF-β) signal transduction pathway. They are designed for any collegiate-level course that presents the basic steps of the prototypical pathway. Courses that might employ these animations include Introductory Biology, Cell Biology, Molecular Biology, Biochemistry, Developmental Biology, Immunology, Physiology, and Pharmacology.


J. D. Thatcher, The TGF-β Signal Transduction Pathway. Sci. Signal. 3, tr4 (2010).

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882