LetterAntibodies

Response to Comment on “Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs”

Science Signaling  20 Jul 2010:
Vol. 3, Issue 131, pp. lc2
DOI: 10.1126/scisignal.3131lc2

You are currently viewing the abstract.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Abstract

Moens and colleagues express concern that our report of phosphorylation of p38–regulated/activated protein kinase (PRAK) at Ser93 in senescent cells may be incorrect as a result of their inability to detect phosphorylated PRAK with the same antibody. We provide additional characterization of the antibody that we used and show that there is a 42-kilodalton phosphoprotein detected by this antibody, but that this phosphoprotein may not be PRAK.

View Full Text

Related Content