Science Signaling Podcast: 5 October 2010

Science Signaling  05 Oct 2010:
Vol. 3, Issue 142, pp. pc18
DOI: 10.1126/scisignal.3142pc18

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This is a conversation with Dirk Hermann about a Research Article published in the 5 October 2010 issue of Science Signaling. ElAli and Hermann report that apolipoprotein E (ApoE) regulates ATP-binding cassette (ABC) drug transporters in the ischemic brain, thereby controlling brain-to-blood drug distribution. Inhibition of ApoE signaling is a potential clinical strategy for enhancing the delivery of neuroprotective drugs to the brain after ischemic stroke.

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