Mechanisms of Sperm-Egg Interactions: Between Sugars and Broken Bonds

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Sci. Signal.  05 Oct 2010:
Vol. 3, Issue 142, pp. pe35
DOI: 10.1126/scisignal.3142pe35

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A model of the early events of mammalian fertilization has emerged during the past 30 years. However, studies during the past decade have used newly available mouse models to readdress these processes. Here, we will consider these new data in light of the existing model and point to areas of reconciliation and of controversy.

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