PresentationHormone Signaling

Hormone Resistance at the Clinical Level

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Sci. Signal.  12 Oct 2010:
Vol. 3, Issue 143, pp. pt1
DOI: 10.1126/scisignal.3143pt1

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A presentation from the third NICHe Conference, “New Inroads to Child Health—Child Health and Signal Transduction,” Varberg, Sweden, 21 to 23 May 2010.


This presentation introduces clinical aspects of hormone resistance through a number of case studies that illustrate how molecular defects at various steps in hormone production, signaling, or responsiveness can produce disease in humans. The presentation also shows how careful phenotyping of such patients has triggered decades of translational research.

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