Science Signaling Podcast: 23 November 2010

Sci. Signal., 23 November 2010
Vol. 3, Issue 149, p. pc21
DOI: 10.1126/scisignal.3149pc21

Science Signaling Podcast: 23 November 2010

  1. Elaine F. Reed1 and
  2. Annalisa M. VanHook2
  1. 1UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.
  2. 2Web Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.


This is a conversation with Elaine Reed about a Research Article published in the 23 November 2010 issue of Science Signaling. Zhang and colleagues report that human leukocyte antigen I (HLA-I) partners with the integrin β4 subunit to induce migration and proliferation of endothelial cells. Interactions between HLA-I and the integrin β4 subunit may contribute to transplant vasculopathy and so represent a potential target for therapies to limit transplant rejection.


E. F. Reed and A. M. VanHook, Science Signaling Podcast: 23 November 2010. Sci. Signal. 3, pc21 (2010).
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