Editorial GuideCell Biology

Focus Issue: Metabolic Signals

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Sci. Signal.  07 Dec 2010:
Vol. 3, Issue 151, pp. eg12
DOI: 10.1126/scisignal.3151eg12

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This Focus Issue of Science Signaling complements the Science Special Issue on Metabolism (http://www.sciencemag.org/special/metabolism) by turning attention to the pathways and molecules involved in controlling cellular metabolic processes. Highlights include an unexpected role in triggering apoptosis for the insulin receptor and the related IGF-1 receptor (known for their roles in metabolism and growth), a role for lipids as cellular sensors of glucose metabolism, and a mechanism whereby cells can survive oxidative stress by shifting the activity of the cell’s protein degradation complex.

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