Science Signaling Podcast: 5 April 2011

Sci. Signal., 5 April 2011
Vol. 4, Issue 167, p. pc7
DOI: 10.1126/scisignal.2002027

Science Signaling Podcast: 5 April 2011

  1. Sophie Ugolini1,2,3,
  2. Eric Vivier1,2,3,4, and
  3. Annalisa M. VanHook5
  1. 1Centre d’Immunologie de Marseille-Luminy, Université de la Méditerranée, Campus de Luminy case 906, 13288 Marseille, France.
  2. 2INSERM U631, Marseille, France.
  3. 3CNRS, UMR6102, Marseille, France.
  4. 4Assistance Publique – Hôpitaux de Marseille, Hôpital de la Conception, 13385 Marseille, France.
  5. 5Web Editor, Science Signaling, American Association for the Advancement of Science, 1200 New York Avenue, N.W., Washington, DC 20005, USA.

Abstract

This Podcast features a conversation with the senior authors of a Research Article published in the April 5 issue of Science Signaling. Sophie Ugolini and Eric Vivier discuss their team’s finding that signaling through inhibitory NK cell receptors determines the distribution of activating receptors, which, in turn, determines the responsiveness of the cells to activating stimuli. This finding suggests that inhibitory receptors can affect membrane receptor organization and hence the responsiveness of NK cells.

Citation:

S. Ugolini, E. Vivier, and A. M. VanHook, Science Signaling Podcast: 5 April 2011. Sci. Signal. 4, pc7 (2011).
Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882