Vol 4, Issue 182
- The Deacetylase SIRT1 Promotes Membrane Localization and Activation of Akt and PDK1 During Tumorigenesis and Cardiac Hypertrophy
Deacetylation of Akt and its activating kinase PDK1 promotes cell growth in physiological and pathological settings.
- PreTCR and TCRγδ Signal Initiation in Thymocyte Progenitors Does Not Require Domains Implicated in Receptor Oligomerization
T cell receptor chains lacking oligomerization domains can drive the development of early thymocyte progenitors.