Science Signaling Podcast: 4 October 2011

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Sci. Signal.  04 Oct 2011:
Vol. 4, Issue 193, pp. pc20
DOI: 10.1126/scisignal.2002543

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This Podcast features a conversation with the senior author of a Research Report that was published in Science Express on 15 September 2011. Andre Levchenko discusses his group’s analysis of information flow through a noisy biochemical network. Modeling of the tumor necrosis factor (TNF) signaling network predicted the presence of an information bottleneck early in the network, and these results were confirmed in experiments. These results highlight how populations of cells may be able to overcome noise.

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