11 October 2011
Vol 4, Issue 194

About The Cover

Cover image expansion

Online Cover This week features a Research Article showing that the transcription factor Mad, which is best characterized as an effector of the bone morphogenetic protein (BMP) pathway, also participates in the Wingless pathway. The image shows a mutant fruit fly expressing a form of Mad that is resistant to BMP-induced phosphorylation in the eye. The phenotype of antenna-like tissue growing out of the eye is a developmental defect typical of excess Wingless signaling. [Image: Edward Eivers and Renee H. Choi, University of California Los Angeles, USA]