Research ArticleCancer

Akt and ERK Control the Proliferative Response of Mammary Epithelial Cells to the Growth Factors IGF-1 and EGF Through the Cell Cycle Inhibitor p57Kip2

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Sci. Signal.  06 Mar 2012:
Vol. 5, Issue 214, pp. ra19
DOI: 10.1126/scisignal.2001986

Article Information

vol. 5 no. 214 ra19

PubMed: 
Published By: 
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History: 
  • Received March 4, 2011
  • Accepted February 10, 2012

Author Information

  1. Devin T. Worster1,
  2. Tobias Schmelzle1,*,
  3. Nicole L. Solimini1,,
  4. Eric S. Lightcap2,
  5. Bjorn Millard3,
  6. Gordon B. Mills4,
  7. Joan S. Brugge1,, and
  8. John G. Albeck1
  1. 1Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  2. 2Millennium Pharmaceuticals, Cambridge, MA 02139, USA.
  3. 3Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.
  4. 4Department of Systems Biology, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA.
  1. To whom correspondence should be addressed. E-mail: joan_brugge{at}hms.harvard.edu
  • * Present Address: Novartis Institutes for Biomedical Research, Disease Area Oncology, CH-4002 Basel, Switzerland.

  • Present Address: Department of Genetics, Harvard University Medical School and Division of Genetics, Brigham and Women’s Hospital, Boston, MA 02115, USA.

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