Vol 5, Issue 216
- Cellular Inhibitors of Apoptosis Are Global Regulators of NF-κB and MAPK Activation by Members of the TNF Family of Receptors
Signaling downstream of tumor necrosis factor family receptors hinges on the presence or absence of c-IAP proteins.
Activation of cannabinoid 1 receptors prevents insulin receptors from promoting β-cell survival in the pancreas.
- The Structure of the TLR5-Flagellin Complex: A New Mode of Pathogen Detection, Conserved Receptor Dimerization for Signaling
TLR5 exhibits a distinct ligand-binding mechanism compared with those used by other TLRs.