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Online Cover This week features a Focus Issue that complements the Science Special Issue on Computational Biology. The conceptual image represents the idea that many cellular processes and signaling networks can be described as circuits. [Image: Chris Bickel, AAAS]

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882