18 September 2012
Vol 5, Issue 242

About The Cover

Cover image expansion

Online Cover This week features a Research Resource that applied bioinformatics analysis to a BRCT protein-protein interaction network to identify biological processes and protein complexes that integrate the DNA damage response with regulation of the cell cycle. The image shows a network based on the tandem BRCT-mediated protein interactions. The BRCT domain–containing proteins are indicated in yellow. [Image: Chris Bickel/AAAS, adapted from Nicholas Woods and Alvaro Monteiro, Moffitt Cancer Center, Tampa, FL]