Teaching ResourceCOMPUTATIONAL BIOLOGY

Using Partial Least Squares Regression to Analyze Cellular Response Data

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Sci. Signal.  16 Apr 2013:
Vol. 6, Issue 271, pp. tr7
DOI: 10.1126/scisignal.2003849

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Abstract

This Teaching Resource provides lecture notes, slides, and a problem set for a lecture introducing the mathematical concepts and interpretation of partial least squares regression (PLSR) that were part of a course entitled “Systems Biology: Mammalian Signaling Networks.” PLSR is a multivariate regression technique commonly applied to analyze relationships between signaling or transcriptional data and cellular behavior.

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