Science Signaling Podcast: 11 June 2013

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Sci. Signal.  11 Jun 2013:
Vol. 6, Issue 279, pp. pc15
DOI: 10.1126/scisignal.2004351

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This Podcast features an interview with Brian Button, author of a Research Article that appears in the 11 June 2013 issue of Science Signaling, about a mechanism that helps maintain proper hydration of airway mucus. Airways are protected by a layer of mucus that traps pathogens and toxins and is propelled out of the airways by beating cilia present on the surface of the airway epithelial cells. The consistency of mucus is important for its proper entrapment functions and for efficient clearance from the airways. Button et al. have identified a feedback mechanism whereby epithelial cells maintain airway mucus at an optimal concentration for efficient clearance.

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