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Research ArticleSystems Biology
Interconnected Network Motifs Control Podocyte Morphology and Kidney Function
- Evren U. Azeloglu1,*,
- Simon V. Hardy1,*,†,
- Narat John Eungdamrong1,‡,
- Yibang Chen1,
- Gomathi Jayaraman1,
- Peter Y. Chuang2,
- Wei Fang1,
- Huabao Xiong3,
- Susana R. Neves1,4,
- Mohit R. Jain5,
- Hong Li5,
- Avi Ma’ayan1,
- Ronald E. Gordon6,
- John Cijiang He1,2,§¶, and
- Ravi Iyengar1,4,§¶
- 1Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 2Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 3Immunobiology Center, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 4Systems Biology Center New York, Mount Sinai School of Medicine, New York, NY 10029, USA.
- 5Department of Biochemistry and Molecular Biology, Center for Advanced Proteomics Research, University of Medicine and Dentistry of New Jersey–New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.
- 6Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA.
- ↵¶Corresponding author. E-mail: ravi.iyengar{at}mssm.edu (R.I.); cijiang.he{at}mssm.edu (J.C.H.)
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↵* These authors contributed equally to this work (joint first authors).
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↵† Present address: Université Laval, 2325 Rue de l’Université, Québec, Québec G1V 0A6, Canada.
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↵‡ Present address: New York University Medical Center, New York, NY 10016, USA.
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↵§ These authors contributed equally to this work (joint senior authors).
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Sci. Signal. 04 Feb 2014:
Vol. 7, Issue 311, pp. ra12
DOI: 10.1126/scisignal.2004621
Vol. 7, Issue 311, pp. ra12
DOI: 10.1126/scisignal.2004621
Evren U. Azeloglu
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Simon V. Hardy
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Narat John Eungdamrong
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Yibang Chen
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Gomathi Jayaraman
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Peter Y. Chuang
Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
Wei Fang
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Huabao Xiong
Immunobiology Center, Mount Sinai School of Medicine, New York, NY 10029, USA.
Susana R. Neves
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.Systems Biology Center New York, Mount Sinai School of Medicine, New York, NY 10029, USA.
Mohit R. Jain
Department of Biochemistry and Molecular Biology, Center for Advanced Proteomics Research, University of Medicine and Dentistry of New Jersey–New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.
Hong Li
Department of Biochemistry and Molecular Biology, Center for Advanced Proteomics Research, University of Medicine and Dentistry of New Jersey–New Jersey Medical School Cancer Center, Newark, NJ 07103, USA.
Avi Ma’ayan
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.
Ronald E. Gordon
Department of Pathology, Mount Sinai School of Medicine, New York, NY 10029, USA.
John Cijiang He
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.Division of Nephrology, Department of Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA.
Ravi Iyengar
Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.Systems Biology Center New York, Mount Sinai School of Medicine, New York, NY 10029, USA.
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