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β1 Integrin Inhibition Elicits a Prometastatic Switch Through the TGFβ–miR-200–ZEB Network in E-Cadherin–Positive Triple-Negative Breast Cancer

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Sci. Signal.  11 Feb 2014:
Vol. 7, Issue 312, pp. ra15
DOI: 10.1126/scisignal.2004751

Article Information

vol. 7 no. 312 ra15

PubMed: 
Published By: 
Print ISSN: 
Online ISSN: 
History: 
  • Received September 23, 2013
  • Accepted January 13, 2014

Author Information

  1. Hoa H. Truong1,*,
  2. Jiangling Xiong1,*,
  3. Veerander P. S. Ghotra1,
  4. Ella Nirmala1,
  5. Lizette Haazen1,
  6. Sylvia E. Le Dévédec1,
  7. Hayri E. Balcioğlu1,
  8. Shuning He2,
  9. B. Ewa Snaar-Jagalska2,
  10. Erno Vreugdenhil3,
  11. John H. N. Meerman1,
  12. Bob van de Water1, and
  13. Erik H. J. Danen1,
  1. 1Division of Toxicology, Leiden Academic Center for Drug Research, Leiden University, Leiden 2333CC, the Netherlands.
  2. 2Department of Molecular Cell Biology, Institute of Biology, Leiden University, Leiden 2333CC, the Netherlands.
  3. 3Division of Medical Pharmacology, Leiden Academic Center for Drug Research, Leiden University, Leiden 2333CC, the Netherlands.
  1. Corresponding author. E-mail: e.danen{at}lacdr.leidenuniv.nl
  • * These authors contributed equally to this work.

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