Editors' ChoicePlant biology

A Different Route

Sci. Signal.  04 Mar 2014:
Vol. 7, Issue 315, pp. ec64
DOI: 10.1126/scisignal.2005226

The plant hormone auxin regulates a variety of developmental processes and responses to environmental inputs, often via changes in gene transcription. Xu et al. analyzed a signaling pathway involving ABP1 (auxin-binding protein 1) that affects the cytoskeleton and endocytosis in Arabidopsis without changing gene transcription. Instead, ABP1 functions at the cell surface to bind auxin and a family of membrane kinases, thereby activating intracellular guanosine triphosphatases to initiate important developmental changes in cell shape.

T. Xu, N. Dai, J. Chen, S. Nagawa, M. Cao, H. Li, Z. Zhou, X. Chen, R. De Rycke, H. Rakusová, W. Wang, A. M. Jones, J. Friml, S. E. Patterson, A. B. Bleecker, Z. Yang, Cell surface ABP1-TMK auxin-sensing complex activates ROP GTPase signaling. Science 343, 1025–1028 (2014). [Abstract] [Full Text]