Vol 8, Issue 363
- Activation of TRPV1 channels inhibits mechanosensitive Piezo channel activity by depleting membrane phosphoinositides
Mechanosensitive Piezo channels involved in pain signaling need specific membrane phosphoinositides for activity.
- Single-cell analysis shows that paracrine signaling by first responder cells shapes the interferon-β response to viral infection
Signals produced by early responding cells to viral infection calibrate the immune response of the cell population.