Editorial GuideNoncoding RNAs

Focus Issue: Noncoding RNAs in cancer

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Sci. Signal.  17 Mar 2015:
Vol. 8, Issue 368, pp. eg3
DOI: 10.1126/scisignal.aaa9789

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Through various means, noncoding RNAs regulate the expression of genes, many of which are associated with cellular homeostasis. Noncoding RNAs—especially microRNAs—are critical regulators of the mechanisms underlying numerous processes in cell biology, particularly those involved in the development and progression of cancer. This special issue of Science Signaling sheds light on the physiological and pathophysiological functions of this distinct class of molecules.

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