The rise in computational systems biology approaches for understanding NF-κB signaling dynamics

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Sci. Signal.  14 Jul 2015:
Vol. 8, Issue 385, pp. fs13
DOI: 10.1126/scisignal.aac6503

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A study by Cheng et al. in this issue of Science Signaling highlights the distinct single-cell signaling characteristics conferred by pathways mediated by the adaptor proteins MyD88 and TRIF in the TLR4-dependent activation of the transcription factor nuclear factor κB (NF-κB).

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