A top-notch dilemma: The complex role of NOTCH signaling in osteoarthritis

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Sci. Signal.  21 Jul 2015:
Vol. 8, Issue 386, pp. fs14
DOI: 10.1126/scisignal.aac7862

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A study by Liu et al. in the current issue of Science Signaling explores the complex dual role of NOTCH in the etiology of osteoarthritis by comparing gain-of-function mouse models representing aberrant pathological signaling and transient physiological signaling.

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