Vol 8, Issue 395
- SOCS3 in retinal neurons and glial cells suppresses VEGF signaling to prevent pathological neovascular growth
Enhancing SOCS3 activity in neurons and glial cells in the retina may prevent abnormal blood vessel formation in proliferative retinopathies.
- Dichotomous roles for externalized cardiolipin in extracellular signaling: Promotion of phagocytosis and attenuation of innate immunity
A phospholipid common to mitochondria and bacteria promotes phagocytosis and inhibits cytokine production by macrophages.
- Science Signaling Podcast for 22 September 2015: SOCS3 prevents pathological retinal neovascularization
SOCS3 activity in neural and glial cells of the retina prevents pathological retinal neovascularization.
The protease PCSK6 cleaves the zymogen form of the protease corin, which is responsible for cleavage-mediated activation of the hormone atrial natriuretic peptide.