Editorial GuideCalcium signaling

Focus Issue: The ins and outs of ORAI in immune cells

Sci. Signal.  08 Mar 2016:
Vol. 9, Issue 418, pp. eg3
DOI: 10.1126/scisignal.aaf4957

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This Focus Issue highlights research into cell-specific regulation of store-operated calcium entry through the ORAI/STIM channel complex. Understanding the properties of these channels and how ORAI activity is regulated will lead to a better molecular view of immune cell function and diseases involving the immune system.

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