Focus Issue: New insights in GPCR to G protein signaling

Sci. Signal.  12 Apr 2016:
Vol. 9, Issue 423, pp. eg6
DOI: 10.1126/scisignal.aaf7642

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This Focus Issue highlights new discoveries at the level of the receptor, the α subunit, and the βγ subunit and spans research in yeast on polarized growth and G protein–coupled receptor (GPCR) trafficking, in mice on an orphan GPCR with constitutive activity, and a disease-causing mutation in an α subunit that results in inappropriate GPCR–G protein coupling.

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