Research ArticleDRUG DESIGN

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

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Sci. Signal.  24 May 2016:
Vol. 9, Issue 429, pp. ra53
DOI: 10.1126/scisignal.aad8170

Article Information

vol. 9 no. 429 ra53

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History: 
  • Received November 5, 2015
  • Accepted May 3, 2016

Author Information

  1. Zeynep Madak-Erdogan1,
  2. Sung Hoon Kim2,
  3. Ping Gong1,
  4. Yiru C. Zhao1,
  5. Hui Zhang3,
  6. Ken L. Chambliss3,
  7. Kathryn E. Carlson2,
  8. Christopher G. Mayne4,
  9. Philip W. Shaul3,
  10. Kenneth S. Korach5,
  11. John A. Katzenellenbogen2, and
  12. Benita S. Katzenellenbogen1,*
  1. 1Department of Molecular and Integrative Physiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  2. 2Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  3. 3Center for Pulmonary and Vascular Biology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390–9063, USA.
  4. 4Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
  5. 5National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA.
  1. *Corresponding author. Email: katzenel{at}illinois.edu

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