Introduction to Statistical Methods for Analyzing Large Data Sets: Gene-Set Enrichment Analysis

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Science Signaling  06 Sep 2011:
DOI: 10.1126/scisignal.2001966


This Teaching Resource provides lecture notes, slides, and a problem set for a series of lectures introducing the mathematical concepts behind gene-set enrichment analysis (GSEA) and were part of a course entitled “Systems Biology: Biomedical Modeling.” GSEA is a statistical functional enrichment analysis commonly applied to identify enrichment of biological functional categories in sets of ranked differentially expressed genes from genome-wide mRNA expression data sets.

Full article available 13 September 2011, Vol. 4, Issue 190, pp. tr4