Coupled Transport Protein Systems

Science Signaling  09 Apr 2013:

DOI: 10.1126/scisignal.2003450


This set of animated lessons provides examples of how transport proteins interact in coupled systems to produce physiologic effects. The gastric pumps animation depicts the secretion of hydrochloric acid into the gastric lumen. The animation called glucose absorption depicts glucose absorption by intestinal epithelial cells. The cystic fibrosis conductance transmembrane regulator (CFTR) animation explains how the CFTR functions as a key component of a coupled system of transport proteins that clears the pulmonary system of mucus and inhaled particulates. These animations serve as valuable resources for any collegiate-level course that describes these processes. Courses that might use them include introductory biology, biochemistry, biophysics, cell biology, pharmacology, and physiology.

Full article available 16 April 2013, Vol. 6, Issue 271, tr5