Erratum

Erratum

Ben Chih and Peter Sheiffele

The following correction should be noted for the Perspective "Is Reelin the Answer to Synapse Elimination at the Neuromuscular Junction?"

This Perspective discussed findings published in an article by C. C. Quattrocchi et al. (1). Because of critically flawed data and the inability of others to reproduce the results (2), the article has been retracted (3). Although our discussion of protease-dependent mechanisms in synapse elimination remains valid, the proposed role for Reelin in this process is now unfounded.

References

  1. C. C. Quattrocchi, C. Huang, S. Niu, M. Sheldon, D. Benhayon, J. Cartwright Jr., D. R. Mosier, F. Keller, G. D'Arcangelo, Reelin promotes peripheral synapse elimination and maturation. Science 301, 649-653 (2003). [Abstract] [Full Text]
  2. C. Bidoia, T. Misgeld, E. Weinzierl, M. Buffelli, G. Feng, A. Cangiano, J. W. Lichtman, J. R. Sanes, Comment on "Reelin Promotes Peripheral Synapse Elimination and Maturation". Science 303, 1977 (2004). [Full Text]
  3. C. C. Quattrocchi, C. Huang, S. Niu, M. Sheldon, D. Benhayon, J. Cartwright, Jr., D. R. Mosier, F. Keller, G. D'Arcangelo, Retraction. Science 303, 1974 (2004). [Full Text]