Supplementary Table 2

The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis

(Supplementary Table 2)

Frank H. Yu1 and William A. Catterall1*

1Department of Pharmacology, Mailstop 357280, University of Washington, Seattle, WA 98195�7280, USA.

*Corresponding author. E-mail: wcatt{at}

Table S2. Amino acid alignment of the minimum pores of voltage-gated ion channels.

Alignment of the minimum pore sequences of 143 VGL ion channel was generated by ClustalX and was manually edited. The pore regions of the fourth homologous domain of NaV and CaV channels, the second domain of TPC, the first pore regions of K2P channels, and the mouse mTrp2 channel were used in the alignment.

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Citation: F. H. Yu, W. A. Catterall, The VGL-chanome: A protein superfamily specialized for electrical signaling and ionic homeostasis. Sci. STKE2004, re15 (2004).

© 2004 American Association for the Advancement of Science