Nuclear Receptor and Transcriptional Complex Cycles
(Table 1. Proteins Involved in the Nuclear
Receptor-Chromatin Cycles)

Amy M. Fowler, andElaine T. Alarid*

1University of Wisconsin-Madison, Department of Physiology, 1300 University Ave, Madison, WI 53706. afowler@wisc.edu and alarid@physiology.wisc.edu

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*Corresponding author. E-mail, alarid@physiology.wisc.edu

Table 1. Proteins involved in the nuclear receptor-chromatin cycles. Not all proteins are shown individually in the animation http://stke.sciencemag.org/cgi/content/full/sigtrans;2004/262/tr11/DC1. Bold entries indicate the general name given for either a multiprotein complex or a class of proteins.

Abbreviation Name
ER Estrogen Receptor
hSWI/SNF ATP-dependent chromatin remodeling complex
(shown as SWI/SNF in the animation)
hBRG1
INI1
hBRM1
Brahma-related gene 1 protein
Integrase interactor 1
Brahma protein
HAT
p300
GCN5
Tip60
pCAF
CBP
Histone acetyltransferase
p300
General control positive factor
Tat-interacting protein
p300/CBP associated factor
CREB binding protein
HMT
PRMT1
CARM1
Histone methyltransferase
Protein arginine methyltransferase
Cofactor associated arginine methyltransferase
CoA
SRC1
SRC3
Coactivator
Steroid receptor coactivator 1
Steroid receptor coactivator 3
TAF II
TAF II250
TATA binding protein (TBP)-associated factor
TBP-associated factor of 250 kD
TAF II130
TBP
TFIIA

RNAPII
TBP-associated factor of 130 kD
TATA box-binding protein
Component of the basal transcription machinery
included in RNA polymerase II holoenzyme
RNA polymerase II
E3 ligase

E6AP
MDM2
E3 ubiquitin ligase
(shown as E3 in the animation)
Oncoprotein E6-associated protein
Murine double minute 2
Mediator
Med7
TRAP220

CDK7
(multiprotein complex)
Mediator subunit 7
Thyroid hormone receptor-associated
protein of 220 kD
Cyclin-dependent kinase 7 (subunit of TFIIH)
Elongator
Elp1
Elp3
(multiprotein complex)
Elongator protein 1
Elongator protein 3
APIS

SUG1
AAA ATPase proteins independent of 20S
(19S regulatory component of the proteasome)
Suppressor gene 1
HDAC
HDAC1
HDAC7
HSP70
NuRD
Histone deacetylase
Histone deacetylase 1
Histone deacetylase 7
Heat shock protein of 70 kD
Nucleosome remodeling and histone deactylation
(multiprotein complex, 15 subunits)

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Citation: A. M. Fowler, E. T. Alarid, Nuclear receptor and transcriptional complex cycles. Sci. STKE2004, tr11 (2004).

© 2004 American Association for the Advancement of Science