Cell Signaling Systems: A Course for Graduate Students

Ravi Iyengar*, Maria Diverse-Pierluissi, Daniel Weinstein, andLakshmi Devi

1 Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA.


*Corresponding author. E-mail: ravi.iyengar{at}


This course uses the primary literature to develop a systems-level understanding of the information flow through the various cell signaling pathways and networks. Current areas of research activities in the experimental and theoretical understanding of cell signaling research are highlighted. We recommend that each topic be discussed in a 2-hour lecture, followed by a 2-hour class in which students present an in-depth analysis of one or more primary literature articles. The articles to be presented by the students are selected in consultation with the lecturer to ensure quality of the article and relevance of the article to the topic. The students not presenting are expected to participate in class discussion of the article in a journal, clublike format.

To ensure that each topic is covered by a expert in the field, this course when taught at Mount Sinai School of Medicine is taught by a team of scientists, and the course is divided into six sections with one or two lecturers serving as coordinator and discussion leader for each section.

This Teaching Resource shows the syllabus used to organize this course in Spring 2005 at Mount Sinai School of Medicine. Other instructors wanting to design a similar course may find the General Syllabus a useful starting point. Any students following the Cell Signaling Systems course through STKE will want to access the Spring 2005 Syllabus for Students.

[Access General Syllabus (html)] [Access General Syllabus (Word version)]

[Access Spring 2005 Syllabus (html)] [Access Spring 2005 Syllabus (Word version)]

Educational Details

Learning Resource Type: Syllabus

Context: Undergraduate upper division, graduate, professional (degree program)

Intended Users: Teacher, learner

Intended Educational Use: Teach, learn

Discipline: Cell biology, immunology, developmental biology, neurobiology, biochemistry, biophysics

Keywords: Systems biology, signal transduction, networks

Technical Details

Format: Word, html

Related Resources

Forum: A. Chan, R. Iyengar, S. Aaronson, A. Caplan, S. Salton, M. M. Zhou, Principles of cell signaling and biological consequences. Sci. STKE (Forum, as seen February 2005),;15?FORUM_ID=stkeforum;15.

Limits for Use

Cost: Free

Rights: This material may be downloaded, printed, linked to, and/or redistributed without modification for noncommercial, course-teaching purposes only, provided credit to STKE is included by listing the citation for the teaching resource.


Citation: R. Iyengar, M. Diverse-Pierluissi, D. Weinstein, L. A. Devi, Cell signaling systems: A course for graduate students. Sci. STKE2005, tr3 (2005).

© 2005 American Association for the Advancement of Science