Cell Signaling Systems: A Course for Graduate Students
Syllabus for Mount Sinai School of Medicine Spring 2005

Ravi Iyengar*, Maria Diverse-Pierluissi, Daniel Weinstein, andLakshmi Devi

Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine, New York, NY 10029, USA.

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*Corresponding author. E-mail: ravi.iyengar@mssm.edu

This syllabus is based on the course taught at The Dorothy H. and Lewis Rosenstiel Department of Pharmacology and Biological Chemistry, Mount Sinai School of Medicine (http://www.mssm.edu/pharmacology/) in Spring 2005. Except where noted, all faculty listed are from Mount Sinai School of Medicine and contact information is available from http://www.mssm.edu/gradschool/ and the URLs to their faculty pages are provided below.

1 Christian Schindler is faculty at Columbia University.

2 Neal Lue is faculty at Weill Medical College of Cornell University.

3 Mark Philips is faculty at New York University, http://www.med.nyu.edu/Research/M.Philips-res.html

Section Lecturer (*section coordinator) Faculty Web page
Part 1: Principles of Cell Signaling Systems
General Introduction and Introduction to G Protein-Coupled Receptor (GPCR) Signaling Ravi Iyengar* http://directory.mssm.edu/faculty/facultyInfo.php?id=18800&deptid=30
Growth Factor and Receptor Tyrosine Kinases (RTKs) and the Wnt Pathway Stuart Aaronson http://adsr13.mssm.edu/domains/dept/facultyInfo.epl?objname=cancercenter&user=aarons01
Ras to Mitogen-Activated Protein Kinase (MAPK) Pathways Andrew Chan http://directory.mssm.edu/faculty/facultyInfo.php?id=25685&deptid=10
Kinases Avrom Caplan http://directory.mssm.edu/faculty/facultyInfo.php?id=25381&deptid=30
Phosphatases Stephen Salton http://directory.mssm.edu/faculty/facultyInfo.php?id=18725&deptid=93
Domains in RTKs: Structural Aspects Ming-Ming Zhou http://directory.mssm.edu/faculty/facultyInfo.php?id=29002&deptid=94
Discussion Forum Andrew Chan http://directory.mssm.edu/faculty/facultyInfo.php?id=25685&deptid=10
Part 2: G Protein Signaling
Structure of GPCRs and G Proteins Ravi Iyengar http://directory.mssm.edu/faculty/facultyInfo.php?id=18800&deptid=30
GPCRs Stuart Sealfon http://directory.mssm.edu/faculty/facultyInfo.php?id=18802&deptid=93
G Protein Effectors Maria Diverse http://directory.mssm.edu/faculty/facultyInfo.php?id=31915&deptid=30
Discussion Forum Lakshmi Devi* http://directory.mssm.edu/faculty/facultyInfo.php?id=21352&deptid=30
Part 3: Signal Transduction Through Ion Channels
Ligand-Gated Channels Robert Blitzer http://directory.mssm.edu/faculty/facultyInfo.php?id=17955&deptid=30
Regulation of Ion Channels by G Proteins Maria Diverse* http://directory.mssm.edu/faculty/facultyInfo.php?id=31915&deptid=30
Transient Receptor Protein (TRP) Channels Tibor Rohacs http://directory.mssm.edu/faculty/facultyInfo.php?id=7108&deptid=94
Discussion Forum Maria Diverse* http://directory.mssm.edu/faculty/facultyInfo.php?id=31915&deptid=30
Part 4: Signals with Long-Term Consequences
Proteases and Signaling Sherwin Wilk* http://directory.mssm.edu/faculty/facultyInfo.php?id=5982&deptid=30
Apoptosis Sherwin Wilk* http://directory.mssm.edu/faculty/facultyInfo.php?id=5982&deptid=30
Cytokine Receptors-Janus Kinase and Signal Transducer and Activator of Transcription (JAK-STAT) Signaling Christian Schindler1 http://cumicro2.cpmc.columbia.edu/Micro_Files/Schindler_Lab.html
Toll-Like Receptors Maria Abreu http://directory.mssm.edu/faculty/facultyInfo.php?id=34407&deptid=18
Discussion Forum Sherwin Wilk* http://directory.mssm.edu/faculty/facultyInfo.php?id=5982&deptid=30
Part 5: Regulation of Transcription and Translation
Nuclear Transactivators and Repressors Zhen-Qiang Pan http://directory.mssm.edu/faculty/facultyInfo.php?id=27449&deptid=10
Chromatin Remodeling Neal Lue2 http://www.med.cornell.edu/research/nflue/index.html
Nuclear Receptors Reshma Taneja http://directory.mssm.edu/faculty/facultyInfo.php?id=29099&deptid=20
Regulation of Translation Emmanuel Landau http://directory.mssm.edu/faculty/facultyInfo.php?id=17853&deptid=30
Discussion Forum Daniel Weinstein* http://directory.mssm.edu/faculty/facultyInfo.php?id=23861&deptid=30
Part 6: Recent Advances in Signaling Research
Modeling of Signaling Networks Ravi Iyengar http://directory.mssm.edu/faculty/facultyInfo.php?id=18800&deptid=30
Assembly and Organization of Macromolecular Complexes Ravi Iyengar http://directory.mssm.edu/faculty/facultyInfo.php?id=18800&deptid=30
Regulation of Complexes by Cytoskeletal Elements Dan Felsenfeld http://directory.mssm.edu/faculty/facultyInfo.php?id=23677&deptid=30
Imaging Signaling Reactions in the Live Cell Mark Philips3
Discussion Forum Lakshmi Devi* and Maria Diverse* http://directory.mssm.edu/faculty/facultyInfo.php?id=21352&deptid=30
http://directory.mssm.edu/faculty/facultyInfo.php?id=31915&deptid=30
Part 7: Systems Biology of Signaling
Mesodermal Differentiation Daniel Weinstein* http://directory.mssm.edu/faculty/facultyInfo.php?id=23861&deptid=30
Sensory Systems Robert Margolskee http://directory.mssm.edu/faculty/facultyInfo.php?id=27365&deptid=30
Long-Term Potentiation (LTP) Robert Blitzer http://directory.mssm.edu/faculty/facultyInfo.php?id=17955&deptid=30
Discussion Forum Marianna Max http://directory.mssm.edu/faculty/facultyInfo.php?id=27436&deptid=94
Wrap-up Discussion Forum Ravi Iyengar* http://directory.mssm.edu/faculty/facultyInfo.php?id=18800&deptid=30

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Citation: R. Iyengar, M. Diverse-Pierluissi, D. Weinstein, L. A. Devi, Cell signaling systems: A course for graduate students. Sci. STKE2005, tr3 (2005).

© 2005 American Association for the Advancement of Science