Protein Domains that Interact with Receptor Tyrosine Kinases:
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These slides are intended for a class covering insights gained from structural analysis of the regulation of receptor tyrosine kinases and is part of the course �Cell Signaling Systems: A Course for Graduate Students�. The lecture begins with an overview of the many protein domains thus far implicated in cell signaling and then describes in detail the phosphotyrosine-binding domain (PTB). The application of structural information to rational drug design by targeting protein interaction domains is also covered.
Learning Resource Type: PowerPoint slides
Context: Undergraduate upper division, graduate, professional (degree program)
Intended Users: Teacher, learner
Intended Educational Use: Teach, learn, plan
Discipline: Molecular biology, cell biology, biochemistry, structural biology, pharmacology
Keywords: SH2 domain, PTB domain, protein structure, signal transduction
Size: 10.4 MB
Requirements: Microsoft PowerPoint
Limits for Use
Rights: This material may be downloaded for noncommercial, course-teaching purposes only, provided credit to STKE is included by listing the citation for the Teaching Resource.
Citation: M.-M. Zhou, Protein domains that interact with receptor tyrosine kinases: Structural aspects. Sci. STKE2005, tr9 (2005).