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Analysis of Metagene Portraits Reveals Distinct Transitions During Kidney Organogenesis

Igor F. Tsigelny, Valentina L. Kouznetsova,3† Derina E. Sweeney,3 Wei Wu,3 Kevin T. Bush,3 Sanjay K. Nigam

1Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093–0505, USA.

2San Diego Supercomputer Center, University of California, San Diego, La Jolla, CA 92093–0505, USA.

3Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA 92093–0693, USA.

4Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla, CA 92093–0693, USA.

5Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093–0693, USA.

6John and Rebecca Moores UCSD Cancer Center, School of Medicine, University of California, San Diego, La Jolla, CA 92093–0693, USA.

These authors contributed equally to this work.

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Submitted: 23 July 2008

Accepted: 22 November 2008

Published online: 4 December 2008 as 10.1126/scisignal.1163630

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Final publication: 9 December 2008, volume 1, issue 49, page ra16

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*To whom correspondence should be addressed. E-mail: snigam{at}ucsd.edu (S.K.N.) and itsigeln{at}ucsd.edu (I.F.T.)

Citation: I. F. Tsigelny, V. L. Kouznetsova, D. E. Sweeney, W. Wu, K. T. Bush, S. K. Nigam, Analysis of metagene portraits reveals distinct transitions during kidney organogenesis. Sci. Signal.1, ra16 (2008).

© 2008 American Association for the Advancement of Science