Supplementary Materials

Supplementary Materials for:

Involvement of the Protein Kinase CK2 in the Regulation of Mammalian Circadian Rhythms

Yoshiki Tsuchiya, Makoto Akashi, Mitsuhiro Matsuda, Kyoko Goto, Yoshihiko Miyata, Koichi Node, Eisuke Nishida*

*To whom correspondence should be addressed. E-mail: L50174{at}sakura.kudpc.kyoto-u.ac.jp

This PDF file includes:

  • Fig. S1. Circadian oscillation of the Bmal1-Luc reporter activity is affected by DRB.
  • Fig. S2. CK2 inhibition dampens circadian oscillation of Per2 mRNA expression.
  • Fig. S3. Circadian oscillation of phosphorylation of CDC37 at a CK2 site.
  • Fig. S4. The N-terminal half of PER2 does not bind to CKIε.
  • Fig. S5. Expression of Per2-WT and S53A are comparable.
  • Fig. S6. CKIε is coimmunoprecipitated with CK2β in the presence of PER2.

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Citation: Y. Tsuchiya, M. Akashi, M. Matsuda, K. Goto, Y. Miyata, K. Node, E. Nishida, Involvement of the protein kinase CK2 in the regulation of mammalian circadian rhythms. Sci. Signal.2, ra26 (2009).

© 2009 American Association for the Advancement of Science