Supplementary Materials

Supplementary Materials for:

Neuronal and Intestinal Protein Kinase D Isoforms Mediate Na+ (Salt Taste)�Induced Learning

Ya Fu, Min Ren, Hui Feng, Lu Chen, Zeynep F. Altun, Charles S. Rubin*

*To whom correspondence should be addressed. E-mail: rubin{at}

This PDF file includes:

  • Fig. S1. Domain organization of PKDs and PKCε.
  • Fig. S2. Food suppresses Na+-induced learning.
  • Fig. S3. Both neuronal DKF-2B and intestinal DKF-2A are essential for Na+-induced, aversive learning.
  • Fig. S4. WT transgenes rescue learning defects in TPA-1� and EGL-8�deficient animals.
  • Fig. S5. PLC-DAG-PKC-PKD signaling modules in neurons and intestinal cells cooperatively mediate Na+-induced, associative learning.
  • Fig. S6. Animals differentially expressing DKF-2A are not generally compromised in sensing or learning.
  • Fig. S7. DKF-2B�GFP and WT DKF-2B have similar properties.

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Citation: Y. Fu, M. Ren, H. Feng, L. Chen, Z. F. Altun, C. S. Rubin, Neuronal and intestinal protein kinase D isoforms mediate Na+ (salt taste)�induced learning. Sci. Signal.2, ra42 (2009).

© 2009 American Association for the Advancement of Science