Supplementary Materials

Supplementary Materials for:

Cooperativity Between T Cell Receptor Complexes Revealed by Conformational Mutants of CD3ε

Nuria Martínez-Mart�n, Ruth M. Risueño, Antonio Morreale, Irene Zaldívar, Elena Fern�ndez-Arenas, Fernando Herranz, Angel R. Ortiz, Balbino Alarcón*

*To whom correspondence should be addressed. E-mail: balarcon{at}

This PDF file includes:

  • Fig. S1. RMSD evolution of CD3ε-CD3δ dimers.
  • Fig. S2. Comparison of unbound and antibody-bound CD3ε-CD3δ dimers.
  • Fig. S3. Comparison of the structures of mouse and human CD3ε-CD3δ dimers.
  • Fig. S4. Expression of FLAG-tagged mutants of CD3ε in Ly5.2+ thymocytes from bone marrow chimeras.
  • Movie descriptions

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Other Supplementary Material for this manuscript includes the following:</strong

Movies S1 and S2

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Format: Video Clip (m4v) (Zipped)

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Citation: N. Martínez-Martín, R. M. Risue�o, A. Morreale, I. Zaldívar, E. Fernández-Arenas, F. Herranz, A. R. Ortiz, B. Alarcón, Cooperativity between T cell receptor complexes revealed by conformational mutants of CD3εSci. Signal. 2, ra43 (2009).

© 2009 American Association for the Advancement of Science