Supplementary Materials

Sci. Signal., 2 March 2010
DOI: 10.1126/scisignal.2000502
Supplementary Materials for:

Polycomb Group Proteins as Epigenetic Mediators of Neuroprotection in Ischemic Tolerance

Martha Stapels, Chelsea Piper, Tao Yang, Minghua Li, Cheri Stowell, Zhi-gang Xiong, Julie Saugstad, Roger P. Simon,* Scott Geromanos, James Langridge, Jing-quan Lan, An Zhou*

*To whom correspondence should be addressed. E-mail: azhou{at}downeurobiology.org (A.Z.) and rsimon{at}downeurobiology.org (R.P.S.)

This PDF file includes:

  • Fig. S1. Chromatographic peak area measurement.
  • Fig. S2. Immunohistochemistry of H2A and BMI1.
  • Fig. S3. Knocking down or overexpressing PcG proteins.
  • Fig. S4. Changes in abundance of RING2 and mUb-H2A in mouse brains and in NS20Y cells.
  • Table S1. Total identified and quantified proteins in mouse cortex.
  • Table S2. Numbers of proteins that change in abundance under each condition.
  • Table S3. Proteins that change in abundance under ischemic-preconditioned condition.
  • Table S4. Proteins that change in abundance under ischemic-tolerant condition.
  • Table S5. Proteins that change in abundance under ischemic-injured condition.
  • Table S6. Proteins that change in abundance under a unique brain ischemic condition or more than one condition.
  • Table S7. Biological processes presented by proteins that change in abundance under different conditions of brain ischemia.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size: 8.5 MB


Citation: M. Stapels, C. Piper, T. Yang, M. Li, C. Stowell, Z.-g. Xiong, J. Saugstad, R. P. Simon, S. Geromanos, J. Langridge, J.-q. Lan, A. Zhou, Polycomb group proteins as epigenetic mediators of neuroprotection in ischemic tolerance. Sci. Signal. 3, ra15 (2010).

© 2010 American Association for the Advancement of Science

Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882