LRP6 Mediates cAMP Generation by G Protein–Coupled Receptors Through Regulating the Membrane Targeting of Gαs
Mei Wan,* Jun Li, Katie Herbst, Jin Zhang, Bing Yu, Xiangwei Wu, Tao Qiu, Weiqi Lei, Charlotta Lindvall, Bart O. Williams, Hairong Ma, Fengjie Zhang, Xu Cao*
*To whom correspondence should be addressed. E-mail:(M.W.); (X.C.)
This PDF file includes:
- Fig. S1. Mass spectrometric identification of a PKA phosphorylation site in LRP6.
- Fig. S2. Identification of the Gαs interaction domain in LRP6.
Format: Adobe Acrobat PDF
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Citation: M. Wan, J. Li, K. Herbst, J. Zhang, B. Yu, X. Wu, T. Qiu, W. Lei, C. Lindvall, B. O. Williams, H. Ma, F. Zhang, X. Cao, LRP6 Mediates cAMP Generation by G Protein–Coupled Receptors Through Regulating the Membrane Targeting of Gαs. Sci. Signal. 4, ra15 (2011).